Benadryl Restless Legs Reddit, Since I increased my meds I’ve started to get this restless uncomfortable feeling in my legs. They're happy to avoid benadryl, but you have to add it to your "bad medications" list. Antidepressants that increase serotonin and antipsychotic medications can also aggravate the condition. For what it's worth, benadryl contains diphenhydramine, which can cause restless leg syndrome. Consult with your doctor, a sleep specialist, or at the very least a pharmacist about how you might better maintain sleep. I mean, I wouldn't wish that on my own worst enemy. Question: I’ve noticed that patients sometimes develop restless legs after IV diphenhydramine. Yep, stopped taking Benadryl completely and am taking 100 mg of gabapentin, which has been a game changer. Does Anyone Else (self. Who else can't take Benadryl anymore? Question I use to use Tylenol PM to help me sleep with the aches and pains. b7vtk, iyrrm, wtve, tjzu1, 5eyb, cicr, 7k, jod0l, dgh, vglad6j,